Who wins the NFL Week 2 game?

The Tennessee Titans and Buffalo Bills play on Monday, September 19 in an NFL Week 2 matchup.

Which team will get the victory?

Check out these NFL Week picks and predictions for the game, which can be seen at 4:15 p.m. MST on ESPN.

The Bills are 9.5 point favorites in the game.

NFL Week 2 picks, predictions:

Jeremy Clough writes: “The Titans will certainly be motivated after losing to the Giants in Week 1. Being motivated won’t be enough against the Bills.”

Bookies.com: Get the under on Titans vs. Bills

Bill Speros writes: “The Bills are coming off an extended layoff after their Week 1 opener Thursday night against the Rams. Expect a raucous and well-oiled crowd in Buffalo. Many will be bruised without getting hit after a series of table-top swoons in parking lot The Titans were KO’d at home in the Divisional Round. More importantly, they didn’t improve much in the offseason, as evidenced Sunday against the Giants. The line is moving in the wrong direction. We were shut out in the under at 51 before the Titans beat the Giants. It’s since climbed to 49.5. So if you missed that window, look for the Bills to get the big cover at home for the best NFL Week 2 bets.”

More: NFL Week 2 odds: point spreads, money, over/under for Week 2 of NFL schedule games

Can Ryan Tannehill and the Tennessee Titans beat the Buffalo Bills in NFL Week 2?

Draft Kings: Bills will be covered in the game against the Titans

He writes: “Allen and the Bills looked unstoppable against a team coming off a Super Bowl victory. A team coming off a Giants loss — Derrick Henry or no Derrick Henry — should make quick work of them , especially if the defensive line can keep up the same pressure Monday against Tannehill that they brought last Thursday.”

ESPN: The Bills have an 81.1% chance to win the game

The site’s Football Power Index gives the Titans an 18.7% range to pull off the win.

More: NFL Week 2 schedule, TV info: How to watch NFL Week 2 games

Pro Football Network: Get the Bills against the spread against the Titans

BJ Rudell writes: “As mentioned above, the AFC South remains wide open and the outlook will likely remain hazy after this next slate. That’s because Tennessee will face the first of many (yes, many) brutally tough opponents of — a big reason I picked them not to win their division this year. Barring something unforeseen, Buffalo should win by 18+.”

Vegas Odds: Go with the Bills to cover against the Titans

Annie Adkins writes: “The Bills are going to win this game, we have no doubt about it. And they’re going to do it by a wide margin, covering the spread along the way. We expect the Titans to do it in a hurry, though, with Henry to probably score a TD or two.”

More: NFL power rankings Week 2: Cardinals, Bengals, Patriots, Packers plummet after Week 1 losses

Contact Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.

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This article originally appeared in the Arizona Republic: Tennessee Titans picks vs. Buffalo Bills, NFL Week 2 game predictions

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