Who wins the NFL Week 1 game?

The San Francisco 49ers and Chicago Bears play Sunday in a Week 1 NFL matchup.

Which team will get the victory?

Check out these NFL Week picks and predictions for the game, which can be seen at 10 a.m. MST on Fox.

The 49ers are 6.5 point favorites in the game.

NFL Week 1 picks, predictions:

Tyler Sullivan writes: “The 49ers should be viewed as a significant favorite against Chicago. The Bears have a new coach and a second-year quarterback who lacks weapons around him, so 2022 could be another down year. continue that rebuild. San Francisco was also 8-4 ATS on the road in 2021.”

Jason Katz writes: “Unlike the aforementioned Jets, the Bears have done almost nothing to help their second-year signal-caller. Fields’ WR1 is Darnell Mooney, and his WR2 and WR3 are Byron Pringle and Equanimeous St. Brown. The only wide receiver Chicago drafted was 25-year-old special aid Velus Jones Jr. A touchdown is a heavy price to pay on the road, but I have no confidence in the Bears this season.”

Week 1 NFL Odds:

Bookies.com: Get the under on the 49ers vs. Bears game

Bill Speros writes: “The 49ers, Deebo Samuel and Jimmy Garoppolo remain stuck with each other – at least as of this writing. The situation hasn’t changed since early this offseason. Bears hire Matt Eberfus as coach. Brought in a new offensive and defensive coordinator. 49ers reached NFC title game before blowing 10-point lead to Rams. Samuel wants trade while Niners want trade Jimmy G. Garoppolo continues to heal from shoulder surgery off-season and may well be moved once he is deemed fully healthy.”

Fansided: Bears 23, 49ers 20

Matt Verderame predicts Chicago to beat San Francisco in Week 1 of the NFL season at home.

More: When does the NFL season start? Here’s the Week 1 schedule and how to watch games on TV

Can Justin Fields and the Chicago Bears beat the San Francisco 49ers in a Week 1 NFL matchup?

Walter Football: Go with the 49ers vs. Bears in Week 1

He writes: “The 49ers are the game because the Bears are absolutely terrifying. I’ll be shocked if they’re not a third-place team this year.”

ESPN: The 49ers have a 72.4% chance to win

The site gives the Bears a 27.3% chance to win Week 1.

More: NFL power rankings ahead of Week 1: Los Angeles Rams, Buffalo Bills open NFL season on top

More: Super Bowl 57 odds: Preseason betting odds for every NFL team to win the 2022-2023 Super Bowl

WSN: Take the Bears by the points against the 49ers

Mike Lukas writes: “New Chicago Bears coach Matt Eberflus is a 52-year-old defensive specialist who should match up against this historic defensive force, now with two rookie starters in the secondary – SS Jaquan Brisker and CB Kyler Gordon. young team QB’d by 23-year-old OSU alum Justin Fields, who struggled there in his rookie season, a born winner ready to win. the spread, even though the Niners will probably win it outright.”

Brendan Danaher writes: “Kyle Shanahan’s explosive offensive scheme will be too much for the Bears’ middling defense to handle. Justin Fields doesn’t have enough weapons to overwhelm the 49ers’ defense under up-and-coming defensive coordinator DeMeco Ryans. As If the task wasn’t difficult enough, the Bears also have a new coach in Matt Eberflus. The Bears will be lucky to win more than six games this season and this won’t be one of them.”

Highest Paid NFL Players in 2022:

Contact Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.

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This article originally appeared in the Arizona Republic: San Francisco 49ers vs. Chicago Bears picks, NFL Week 1 predictions

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